OS migration From Linux RH 4.5 to RH 6.x

Hi all,

To migrate the OS system from the linux RH version 4.5 to linux RH version 6.x, which is the most secure and safest to realize this scenario?

Knowing that the version of SAP ECC is  6.0 NUC  with SP level:

SAP_BASIS  700  0011 SAPKB70011

SAP_ABA 700 0011 SAPKA70011

SAP_BW 700 0012 SAPKW70012

SAP_AP 700 0008 SAPKNA7008

SAP_APPL 600 0009 SAPKH60009

SAP_HR 600 0018 SAPKE60018

And the version of the database is Oracle 10.2.0.2.

Thank you in advance.